Secretory Leucoprotease Inhibitor Prevents LPS-induced IκBalpha Degradation without affecting Phosphorylation or Ubiquitination
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منابع مشابه
Secretory leucoprotease inhibitor binds to NF-κB binding sites in monocytes and inhibits p65 binding
Secretory leucoprotease inhibitor (SLPI) is a nonglycosylated protein produced by epithelial cells. In addition to its antiprotease activity, SLPI has been shown to exhibit antiinflammatory properties, including down-regulation of tumor necrosis factor alpha expression by lipopolysaccharide (LPS) in macrophages and inhibition of nuclear factor (NF)-kappaB activation in a rat model of acute lung...
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تاریخ انتشار 2002